Hongbin. Ji, et.al., LKB1 modulates lung cancer differentiation and metastasis., Nature, 2007, 448

http://rdf.ncbi.nlm.nih.gov/pubmed/17676035

Hongbin. Ji, et.al., LKB1 modulates lung cancer differentiation and metastasis., Nature, 2007, 448

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased metastatic potential_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0001272I129P2OlaHsd129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnKrasKrastm4TyjTrp53tm1Brn
• increased lung adenocarcinoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Kras<tm4Tyj>/Kras<+>
  http://metadb.riken.jp/0002027I129Sv129S4SvJaeC57BL6FVBNSJLCdkn2atm1RdpCdkn2atm1RdpKrastm4TyjKrasKrasKrastm4TyjCdkn2atm1Rdp
• increased lung tumor incidence_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Rdp>/Stk11<tm1.1Rdp>
  http://metadb.riken.jp/0008014I129S4SvJae129S6SvEvTacC57BL6FVBNKrastm4TyjKrasStk11tm11RdpStk11tm11RdpKrastm4TyjStk11tm11RdpKras
• premature death_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S6SvEvTacC57BL6FVBNCdkn2atm21RdpCdkn2atm21RdpTrp53tm1BrnTrp53tm1BrnCdkn2atm21RdpTrp53tm1Brn
• increased lung adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>
  http://metadb.riken.jp/0002027I129S4SvJaeC57BL6FVBNKrastm4TyjKrasKrastm4TyjKras
• increased lung adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0002027I129P2OlaHsd129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnKrasKrastm4TyjTrp53tm1Brn
• increased metastatic potential_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Rdp>/Stk11<tm1.1Rdp>
  http://metadb.riken.jp/0001272I129S4SvJae129S6SvEvTacC57BL6FVBNKrastm4TyjKrasStk11tm11RdpStk11tm11RdpKrastm4TyjStk11tm11RdpKras
• premature death_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Rdp>/Stk11<tm1.2Rdp>
  http://metadb.riken.jp/0002083I129S4SvJae129S6SvEvTacC57BL6FVBNKrastm4TyjKrasStk11tm11RdpStk11tm12RdpStk11tm12RdpKrastm4TyjKrasStk11tm11Rdp
• premature death_Kras<tm4Tyj>/Kras<+>
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6FVBNKrastm4TyjKrasKrastm4TyjKras
• increased lung large cell carcinoma incidence_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Rdp>/Stk11<tm1.2Rdp>
  http://metadb.riken.jp/0008718I129S4SvJae129S6SvEvTacC57BL6FVBNKrastm4TyjKrasStk11tm11RdpStk11tm12RdpStk11tm12RdpKrastm4TyjKrasStk11tm11Rdp
• increased lung adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Rdp>/Stk11<tm1.2Rdp>
  http://metadb.riken.jp/0002027I129S4SvJae129S6SvEvTacC57BL6FVBNKrastm4TyjKrasStk11tm11RdpStk11tm12RdpStk11tm12RdpKrastm4TyjKrasStk11tm11Rdp
• increased metastatic potential_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>
  http://metadb.riken.jp/0001272I129S4SvJae129S6SvEvTacC57BL6FVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasKrastm4TyjCdkn2atm21RdpKras
• premature death_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S4SvJaeC57BL6FVBNKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnKrasKrastm4TyjTrp53tm1Brn
• premature death_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>
  http://metadb.riken.jp/0002083I129S4SvJae129S6SvEvTacC57BL6FVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasKrastm4TyjCdkn2atm21RdpKras
• premature death_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Rdp>/Stk11<tm1.1Rdp>
  http://metadb.riken.jp/0002083I129S4SvJae129S6SvEvTacC57BL6FVBNKrastm4TyjKrasStk11tm11RdpStk11tm11RdpKrastm4TyjStk11tm11RdpKras
• premature death_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Kras<tm4Tyj>/Kras<+>
  http://metadb.riken.jp/0002083I129Sv129S4SvJaeC57BL6FVBNSJLCdkn2atm1RdpCdkn2atm1RdpKrastm4TyjKrasKrasKrastm4TyjCdkn2atm1Rdp
• increased lung large cell carcinoma incidence_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Rdp>/Stk11<tm1.1Rdp>
  http://metadb.riken.jp/0008718I129S4SvJae129S6SvEvTacC57BL6FVBNKrastm4TyjKrasStk11tm11RdpStk11tm11RdpKrastm4TyjStk11tm11RdpKras
• increased lung tumor incidence_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Rdp>/Stk11<tm1.2Rdp>
  http://metadb.riken.jp/0008014I129S4SvJae129S6SvEvTacC57BL6FVBNKrastm4TyjKrasStk11tm11RdpStk11tm12RdpStk11tm12RdpKrastm4TyjKrasStk11tm11Rdp
• increased metastatic potential_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Rdp>/Stk11<tm1.2Rdp>
  http://metadb.riken.jp/0001272I129S4SvJae129S6SvEvTacC57BL6FVBNKrastm4TyjKrasStk11tm11RdpStk11tm12RdpStk11tm12RdpKrastm4TyjKrasStk11tm11Rdp
• increased lung squamous cell carcinoma incidence_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Rdp>/Stk11<tm1.1Rdp>
  http://metadb.riken.jp/0008717I129S4SvJae129S6SvEvTacC57BL6FVBNKrastm4TyjKrasStk11tm11RdpStk11tm11RdpKrastm4TyjStk11tm11RdpKras
• increased lung adenocarcinoma incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>
  http://metadb.riken.jp/0002027I129S4SvJae129S6SvEvTacC57BL6FVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasKrastm4TyjCdkn2atm21RdpKras
• increased lung tumor incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0008014I129P2OlaHsd129S6SvEvTacC57BL6FVBNCdkn2atm21RdpCdkn2atm21RdpTrp53tm1BrnTrp53tm1BrnCdkn2atm21RdpTrp53tm1Brn
• lung hemorrhage_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0001182I129P2OlaHsd129S6SvEvTacC57BL6FVBNCdkn2atm21RdpCdkn2atm21RdpTrp53tm1BrnTrp53tm1BrnCdkn2atm21RdpTrp53tm1Brn
• increased lung adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Rdp>/Stk11<tm1.1Rdp>
  http://metadb.riken.jp/0002027I129S4SvJae129S6SvEvTacC57BL6FVBNKrastm4TyjKrasStk11tm11RdpStk11tm11RdpKrastm4TyjStk11tm11RdpKras
• increased lung squamous cell carcinoma incidence_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Rdp>/Stk11<tm1.2Rdp>
  http://metadb.riken.jp/0008717I129S4SvJae129S6SvEvTacC57BL6FVBNKrastm4TyjKrasStk11tm11RdpStk11tm12RdpStk11tm12RdpKrastm4TyjKrasStk11tm11Rdp