abnormal locomotor behavior_Pink1<tm1Aub>/Pink1<tm1Aub>,Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub

http://metadb.riken.jp/0001392I129SSvEvFVBNPink1tm1AubPink1tm1AubTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAubPink1tm1AubTgPrnpSNCAA53TAAub

abnormal locomotor behavior_Pink1<tm1Aub>/Pink1<tm1Aub>,Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion A, Georg Auburger
  http://metadb.riken.jp/db/mgi_rdf/MGI:3723251
• PTEN induced putative kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1916193

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pink1<tm1Aub>/Pink1<tm1Aub>,Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pink1<tm1Aub>|Tg(Prnp-SNCA*A53T)AAub

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal locomotor behavior
  http://purl.obolibrary.org/obo/MP_0001392

文献

http://purl.org/net/cito/citesAsAuthority

• Suzana. Gispert, et.al., Potentiation of neurotoxicity in double-mutant mice with Pink1 ablation and A53T-SNCA overexpression., Human molecular genetics, 2015, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/25296918