ataxia_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0

http://metadb.riken.jp/0001393I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm

ataxia_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• NAD(P) dependent steroid dehydrogenase-like
  http://metadb.riken.jp/db/mgi_rdf/MGI:1099438
• transgene insertion 25, Albee Messing
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179047

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(GFAP-cre)25Mes|Nsdhl<tm1.1Hrm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• ataxia
  http://purl.obolibrary.org/obo/MP_0001393

文献

http://purl.org/net/cito/citesAsAuthority

• David. Cunningham, et.al., Analysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS development., Human molecular genetics, 2015, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/25652406