David. Cunningham, et.al., Analysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS development., Human molecular genetics, 2015, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/25652406

David. Cunningham, et.al., Analysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS development., Human molecular genetics, 2015, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nsdhl<tm1.1Hrm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5581334

class

http://purl.org/net/cito/citesAsAuthority

• Nsdhl<tm1.1Hrm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5581334

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cerebral cortex morphology_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0000788I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• abnormal hippocampus neuron morphology_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0009939I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• premature death_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0002083I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• ataxia_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0001393I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• abnormal Bergmann glial cell morphology_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0010387I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• abnormal dentate gyrus morphology_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0000812I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• small hippocampus_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0008283I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• hyperkeratosis_Nsdhl<tm1.1Hrm>/Nsdhl<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001242I129S6SvEvTacC57BL6C57BL6NCBANsdhltm11HrmNsdhlTgSox2cre1Amc0TgSox2cre1AmcNsdhlNsdhltm11Hrm
• decreased body size_Nsdhl<tm1.1Hrm>/Nsdhl<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001265I129S6SvEvTacC57BL6C57BL6NCBANsdhltm11HrmNsdhlTgSox2cre1Amc0TgSox2cre1AmcNsdhlNsdhltm11Hrm
• decreased cerebellar granule cell number_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0008924I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• abnormal neuronal stem cell physiology_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0012204I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• abnormal neurite morphology_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0008415I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• abnormal cerebellar granule cell morphology_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0004098I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• abnormal hippocampus morphology_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0000807I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• thin external granule cell layer_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0000873I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• abnormal skeleton morphology_Nsdhl<tm1.1Hrm>/Nsdhl<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0005508I129S6SvEvTacC57BL6C57BL6NCBANsdhltm11HrmNsdhlTgSox2cre1Amc0TgSox2cre1AmcNsdhlNsdhltm11Hrm
• small cerebellum_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0000852I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• abnormal hair growth_Nsdhl<tm1.1Hrm>/Nsdhl<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002073I129S6SvEvTacC57BL6C57BL6NCBANsdhltm11HrmNsdhlTgSox2cre1Amc0TgSox2cre1AmcNsdhlNsdhltm11Hrm
• postnatal growth retardation_Nsdhl<tm1.1Hrm>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001732I129S6SvEvTacC57BL6C57BL6NCBANsdhltm11HrmYTgSox2cre1Amc0TgSox2cre1AmcNsdhltm11Hrm
• abnormal hippocampus granule cell morphology_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0009938I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm
• abnormal Purkinje cell dendrite morphology_Nsdhl<tm1.1Hrm>/Y,Tg(GFAP-cre)25Mes/0
  http://metadb.riken.jp/0008572I129S6SvEvTacC57BL6JFVBNNsdhltm11HrmYTgGFAPcre25Mes0TgGFAPcre25MesNsdhltm11Hrm