hypoactivity_Mecp2<tm1Jae>/Y,Tg(Camk2a-Setdb1)1Akba/0,Tg(Nes-cre)1Atp/0

http://metadb.riken.jp/0001402I129S4SvJaeC57BL6FVBNSJLMecp2tm1JaeYTgCamk2aSetdb11Akba0TgNescre1Atp0TgNescre1AtpMecp2tm1JaeTgCamk2aSetdb11Akba

hypoactivity_Mecp2<tm1Jae>/Y,Tg(Camk2a-Setdb1)1Akba/0,Tg(Nes-cre)1Atp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• methyl CpG binding protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:99918
• transgene insertion 1, Schahram Akbarian
  http://metadb.riken.jp/db/mgi_rdf/MGI:5298875
• transgene insertion 1, Andreas Trumpp
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687337

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mecp2<tm1Jae>/Y,Tg(Camk2a-Setdb1)1Akba/0,Tg(Nes-cre)1Atp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Atp|Mecp2<tm1Jae>|Tg(Camk2a-Setdb1)1Akba

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• hypoactivity
  http://purl.obolibrary.org/obo/MP_0001402

文献

http://purl.org/net/cito/citesAsAuthority

• Yan. Jiang, et.al., Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice., Neuropharmacology, 2011, 60
  http://rdf.ncbi.nlm.nih.gov/pubmed/20869373