Yan. Jiang, et.al., Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice., Neuropharmacology, 2011, 60

http://rdf.ncbi.nlm.nih.gov/pubmed/20869373

Yan. Jiang, et.al., Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice., Neuropharmacology, 2011, 60

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mapt<tm1(Setdb1)Akba>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5298877

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hypoactivity_Mecp2<tm1Jae>/Y,Tg(Camk2a-Setdb1)1Akba/0,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0001402I129S4SvJaeC57BL6FVBNSJLMecp2tm1JaeYTgCamk2aSetdb11Akba0TgNescre1Atp0TgNescre1AtpMecp2tm1JaeTgCamk2aSetdb11Akba
• premature death_Mapt<tm1(Setdb1)Akba>/Mapt<tm1(Setdb1)Akba>,Mecp2<tm1Jae>/Y,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0002083I129S4SvJae129S7SvEvBrdC57BL6FVBNMapttm1Setdb1AkbaMapttm1Setdb1AkbaMecp2tm1JaeYTgNescre1Atp0Mapttm1Setdb1AkbaTgNescre1AtpMecp2tm1Jae
• impaired coordination_Mapt<tm1(Setdb1)Akba>/Mapt<tm1(Setdb1)Akba>,Mecp2<tm1Jae>/Y,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0001405I129S4SvJae129S7SvEvBrdC57BL6FVBNMapttm1Setdb1AkbaMapttm1Setdb1AkbaMecp2tm1JaeYTgNescre1Atp0Mapttm1Setdb1AkbaTgNescre1AtpMecp2tm1Jae
• hypoactivity_Mecp2<tm1Jae>/Y
  http://metadb.riken.jp/0001402I129S4SvJaeC57BL6Mecp2tm1JaeYMecp2tm1Jae
• premature death_Mapt<tm1(Setdb1)Akba>/Mapt<+>,Mecp2<tm1Jae>/Y,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0002083I129S4SvJae129S7SvEvBrdC57BL6FVBNMapttm1Setdb1AkbaMaptMecp2tm1JaeYTgNescre1Atp0MaptTgNescre1AtpMapttm1Setdb1AkbaMecp2tm1Jae
• impaired coordination_Mecp2<tm1Jae>/Y
  http://metadb.riken.jp/0001405I129S4SvJaeC57BL6Mecp2tm1JaeYMecp2tm1Jae
• premature death_Mecp2<tm1Jae>/Y
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6Mecp2tm1JaeYMecp2tm1Jae
• impaired coordination_Mecp2<tm1Jae>/Y,Tg(Camk2a-Setdb1)1Akba/0,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0001405I129S4SvJaeC57BL6FVBNSJLMecp2tm1JaeYTgCamk2aSetdb11Akba0TgNescre1Atp0TgNescre1AtpMecp2tm1JaeTgCamk2aSetdb11Akba
• impaired coordination_Mapt<tm1(Setdb1)Akba>/Mapt<+>,Mecp2<tm1Jae>/Y,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0001405I129S4SvJae129S7SvEvBrdC57BL6FVBNMapttm1Setdb1AkbaMaptMecp2tm1JaeYTgNescre1Atp0MaptTgNescre1AtpMapttm1Setdb1AkbaMecp2tm1Jae
• decreased body weight_Mecp2<tm1Jae>/Y,Tg(Camk2a-Setdb1)1Akba/0,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0001262I129S4SvJaeC57BL6FVBNSJLMecp2tm1JaeYTgCamk2aSetdb11Akba0TgNescre1Atp0TgNescre1AtpMecp2tm1JaeTgCamk2aSetdb11Akba
• decreased body weight_Mecp2<tm1Jae>/Y
  http://metadb.riken.jp/0001262I129S4SvJaeC57BL6Mecp2tm1JaeYMecp2tm1Jae
• premature death_Mecp2<tm1Jae>/Y,Tg(Camk2a-Setdb1)1Akba/0,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6FVBNSJLMecp2tm1JaeYTgCamk2aSetdb11Akba0TgNescre1Atp0TgNescre1AtpMecp2tm1JaeTgCamk2aSetdb11Akba

class

http://purl.org/net/cito/citesAsAuthority

• Mapt<tm1(Setdb1)Akba>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5298877