impaired coordination_Tg(Prnp-TBP*)71-16Xjl/0

http://metadb.riken.jp/0001405FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl

impaired coordination_Tg(Prnp-TBP*)71-16Xjl/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 71-16, Xiao-Jiang Li
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772770

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Prnp-TBP*)71-16Xjl/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp-TBP*)71-16Xjl

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB/N-Tg(Prnp-TBP*)71-16Xjl

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired coordination
  http://purl.obolibrary.org/obo/MP_0001405

文献

http://purl.org/net/cito/citesAsAuthority

• Meyer J. Friedman, et.al., Polyglutamine domain modulates the TBP-TFIIB interaction: implications for its normal function and neurodegeneration., Nature neuroscience, 2007, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/17994014
• Shanshan. Huang, et.al., Neuronal expression of TATA box-binding protein containing expanded polyglutamine in knock-in mice reduces chaperone protein response by impairing the function of nuclear factor-Y transcription factor., Brain : a journal of neurology, 2011, 134
  http://rdf.ncbi.nlm.nih.gov/pubmed/21705419