Meyer J. Friedman, et.al., Polyglutamine domain modulates the TBP-TFIIB interaction: implications for its normal function and neurodegeneration., Nature neuroscience, 2007, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/17994014

Meyer J. Friedman, et.al., Polyglutamine domain modulates the TBP-TFIIB interaction: implications for its normal function and neurodegeneration., Nature neuroscience, 2007, 10

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-TBP*)71-27Xjl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772868
• Tg(Prnp-TBP*)13Xjl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772701
• Tg(Prnp-TBP*)105Xjl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772700
• Tg(Prnp-TBP*)71-16Xjl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772866

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-TBP*)71-27Xjl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772868
• Tg(Prnp-TBP*)13Xjl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772701
• Tg(Prnp-TBP*)105Xjl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772700
• Tg(Prnp-TBP*)71-16Xjl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772866

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• sporadic seizures_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0000951FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• poor grooming_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0001443FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• kyphosis_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0000160FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• poor grooming_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0001443FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• weight loss_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0001263FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• sporadic seizures_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0000951FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• gliosis_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0002183FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• Purkinje cell degeneration_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0000876FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• impaired coordination_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0001405FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• axon degeneration_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0005405FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• limb grasping_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0001513FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• gliosis_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0002183FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• abnormal neurite morphology_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0008415FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• axon degeneration_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0005405FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• abnormal neuron morphology_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0002882FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• impaired coordination_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0001405FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• decreased body size_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0001265FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• abnormal neuron morphology_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0002882FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• neuronal intranuclear inclusions_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0004191FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• gliosis_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0002183FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• limb grasping_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0001513FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• tremors_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0000745FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• poor grooming_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0001443FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• Purkinje cell degeneration_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0000876FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• weight loss_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0001263FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• weight loss_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0001263FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• neuron degeneration_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0003224FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• abnormal neurite morphology_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0008415FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• limb grasping_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0001513FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• abnormal motor coordination/ balance_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0001516FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• tremors_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0000745FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• axon degeneration_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0005405FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• decreased body size_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0001265FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• impaired coordination_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0001405FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• abnormal motor coordination/ balance_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0001516FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• sporadic seizures_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0000951FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• tremors_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0000745FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• premature death_Tg(Prnp-TBP*)71-27Xjl/0
  http://metadb.riken.jp/0002083FVBNTgPrnpTBP7127XjlTgPrnpTBP7127Xjl0TgPrnpTBP7127Xjl
• premature death_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0002083FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• premature death_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0002083FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• Purkinje cell degeneration_Tg(Prnp-TBP*)105Xjl/0
  http://metadb.riken.jp/0000876FVBNTgPrnpTBP105XjlTgPrnpTBP105Xjl0TgPrnpTBP105Xjl
• abnormal neurite morphology_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0008415FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl
• decreased body size_Tg(Prnp-TBP*)71-16Xjl/0
  http://metadb.riken.jp/0001265FVBNTgPrnpTBP7116XjlTgPrnpTBP7116Xjl0TgPrnpTBP7116Xjl