reduced long term potentiation_Tg(Thy1-APPLon)2Vln/0

http://metadb.riken.jp/0001473IFVBNTgThy1APPLon2Vln0TgThy1APPLon2Vln

reduced long term potentiation_Tg(Thy1-APPLon)2Vln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2, Fred Van Leuven
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717495

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Thy1-APPLon)2Vln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Thy1-APPLon)2Vln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• reduced long term potentiation
  http://purl.obolibrary.org/obo/MP_0001473

文献

http://purl.org/net/cito/citesAsAuthority

• Ilse. Dewachter, et.al., Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/11978821
• D. Moechars, et.al., Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain., The Journal of biological chemistry, 1999, 274
  http://rdf.ncbi.nlm.nih.gov/pubmed/10037741