impaired balance_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(Gfap-cre)2Brn/0

http://metadb.riken.jp/0001525I129129S7SvEvBrdFVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrdTrp53tm1BrdTgGfapcre2Brn0Trp53tm1BrdTgGfapcre2BrnRb1tm2Brn

impaired balance_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(Gfap-cre)2Brn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874
• transgene insertion 2, Anton Berns
  http://metadb.riken.jp/db/mgi_rdf/MGI:2671944

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(Gfap-cre)2Brn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>|Tg(Gfap-cre)2Brn|Rb1<tm2Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S7/SvEvBrd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired balance
  http://purl.obolibrary.org/obo/MP_0001525

文献

http://purl.org/net/cito/citesAsAuthority

• S. Marino, et.al., Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum., Genes & development, 2000, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/10783170