S. Marino, et.al., Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum., Genes & development, 2000, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/10783170

S. Marino, et.al., Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum., Genes & development, 2000, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rb1<tm2Brn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1931018
• Tg(Gfap-cre)2Brn
  http://metadb.riken.jp/db/mgi_rdf/MGI:2663939
• Trp53<tm1Brn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1931011

class

http://purl.org/net/cito/citesAsAuthority

• Rb1<tm2Brn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1931018
• Tg(Gfap-cre)2Brn
  http://metadb.riken.jp/db/mgi_rdf/MGI:2663939
• Trp53<tm1Brn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1931011

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• tremors_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0000745I129129S7SvEvBrdFVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrdTrp53tm1BrdTgGfapcre2Brn0Trp53tm1BrdTgGfapcre2BrnRb1tm2Brn
• impaired balance_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0001525I129129S7SvEvBrdFVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrdTrp53tm1BrdTgGfapcre2Brn0Trp53tm1BrdTgGfapcre2BrnRb1tm2Brn
• no abnormal phenotype detected_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0002169I129P2OlaHsdFVBNTrp53tm1BrnTrp53tm1BrnTgGfapcre2Brn0Trp53tm1BrnTgGfapcre2Brn
• circling_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0001394I129129S7SvEvBrdFVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrdTrp53tm1BrdTgGfapcre2Brn0Trp53tm1BrdTgGfapcre2BrnRb1tm2Brn
• ataxia_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0001393I129129S7SvEvBrdFVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrdTrp53tm1BrdTgGfapcre2Brn0Trp53tm1BrdTgGfapcre2BrnRb1tm2Brn
• abnormal gait_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0001406I129129S7SvEvBrdFVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrdTrp53tm1BrdTgGfapcre2Brn0Trp53tm1BrdTgGfapcre2BrnRb1tm2Brn
• increased medulloblastoma incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0006283I129P2OlaHsdFVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrnTrp53tm1BrnTgGfapcre2Brn0TgGfapcre2BrnTrp53tm1BrnRb1tm2Brn
• increased medulloblastoma incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<tm1Brd>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0006283I129129S7SvEvBrdFVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrdTrp53tm1BrdTgGfapcre2Brn0Trp53tm1BrdTgGfapcre2BrnRb1tm2Brn