hyperglycemia_Gt(ROSA)26Sor<tm1(Kcnj11*V59M)Fmas>/Gt(ROSA)26Sor<+>,Tg(Pdx1-cre/Esr1*)#Dam/0

http://metadb.riken.jp/0001559I129S4SvJaeC57BL6CBAGtROSA26Sortm1Kcnj11V59MFmasGtROSA26SorTgPdx1creEsr1Dam0GtROSA26SorTgPdx1creEsr1DamGtROSA26Sortm1Kcnj11V59MFmas

hyperglycemia_Gt(ROSA)26Sor<tm1(Kcnj11*V59M)Fmas>/Gt(ROSA)26Sor<+>,Tg(Pdx1-cre/Esr1*)#Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:5008262

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Kcnj11*V59M)Fmas>/Gt(ROSA)26Sor<+>,Tg(Pdx1-cre/Esr1*)#Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Tg(Pdx1-cre/Esr1*)#Dam|Gt(ROSA)26Sor<tm1(Kcnj11*V59M)Fmas>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• hyperglycemia
  http://purl.obolibrary.org/obo/MP_0001559

文献

http://purl.org/net/cito/citesAsAuthority

• Sharona. Tornovsky-Babeay, et.al., Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells., Cell metabolism, 2014, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/24332968