hyperglycemia_Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell

http://metadb.riken.jp/0001559NODMrkTacTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11Ell

hyperglycemia_Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, John F Elliott
  http://metadb.riken.jp/db/mgi_rdf/MGI:3623968

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• NOD/MrkTac-Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• hyperglycemia
  http://purl.obolibrary.org/obo/MP_0001559

文献

http://purl.org/net/cito/citesAsAuthority

• J. Liu, et.al., Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1*0301, DQB1*0302 transgenic IA(null) NOD mice., Diabetes, 1999, 48
  http://rdf.ncbi.nlm.nih.gov/pubmed/10078545
• John F. Elliott, et.al., Autoimmune cardiomyopathy and heart block develop spontaneously in HLA-DQ8 transgenic IAbeta knockout NOD mice., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/14570980