abnormal embryo development_Pten<tm1Ppp>/Pten<+>,Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0

http://metadb.riken.jp/0001672I129SSvC3HC57BL6CBAPtentm1PppPtenRac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybPtenRac1tm1TybPtentm1Ppp

abnormal embryo development_Pten<tm1Ppp>/Pten<+>,Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• RAS-related C3 botulinum substrate 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97845
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Ppp>/Pten<+>,Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Sox2-cre)1Amc|Rac1<tm2Tyb>|Pten<+>|Rac1<tm1Tyb>|Pten<tm1Ppp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/Sv * C3H * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal embryogenesis/ development
  http://purl.obolibrary.org/obo/MP_0001672

文献

http://purl.org/net/cito/citesAsAuthority

• Isabelle. Migeotte, et.al., Rac1 mediates morphogenetic responses to intercellular signals in the gastrulating mouse embryo., Development (Cambridge, England), 2011, 138
  http://rdf.ncbi.nlm.nih.gov/pubmed/21693517