Isabelle. Migeotte, et.al., Rac1 mediates morphogenetic responses to intercellular signals in the gastrulating mouse embryo., Development (Cambridge, England), 2011, 138

http://rdf.ncbi.nlm.nih.gov/pubmed/21693517

Isabelle. Migeotte, et.al., Rac1 mediates morphogenetic responses to intercellular signals in the gastrulating mouse embryo., Development (Cambridge, England), 2011, 138

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neural tube morphology_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002151I129S4SvJaeC3HC57BL6CBARac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybRac1tm1Tyb
• abnormal developmental patterning_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002084I129S4SvJaeC3HC57BL6CBARac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybRac1tm1Tyb
• abnormal embryonic tissue morphology_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002085I129S4SvJaeC3HC57BL6CBARac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybRac1tm1Tyb
• abnormal mesoderm development_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001680I129S4SvJaeC3HC57BL6CBARac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybRac1tm1Tyb
• increased embryonic tissue cell apoptosis_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0013504I129S4SvJaeC3HC57BL6CBARac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybRac1tm1Tyb
• abnormal embryo development_Pten<tm1Ppp>/Pten<+>,Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001672I129SSvC3HC57BL6CBAPtentm1PppPtenRac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybPtenRac1tm1TybPtentm1Ppp
• cardia bifida_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0004187I129S4SvJaeC3HC57BL6CBARac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybRac1tm1Tyb
• abnormal apoptosis_Pten<tm1Ppp>/Pten<+>,Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001648I129SSvC3HC57BL6CBAPtentm1PppPtenRac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybPtenRac1tm1TybPtentm1Ppp
• impaired somite development_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0009768I129S4SvJaeC3HC57BL6CBARac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybRac1tm1Tyb
• decreased cell proliferation_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000352I129S4SvJaeC3HC57BL6CBARac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybRac1tm1Tyb
• abnormal primitive streak morphology_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002231I129S4SvJaeC3HC57BL6CBARac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybRac1tm1Tyb
• abnormal primitive node morphology_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0004066I129S4SvJaeC3HC57BL6CBARac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybRac1tm1Tyb
• abnormal cell adhesion_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0003566I129S4SvJaeC3HC57BL6CBARac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybRac1tm1Tyb
• increased apoptosis_Nckap1<Gt(RRQ139)Byg>/Nckap1<Gt(RRQ139)Byg>
  http://metadb.riken.jp/0006042I129P2OlaHsdC3HNckap1GtRRQ139BygNckap1GtRRQ139BygNckap1GtRRQ139Byg
• decreased embryo size_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001698I129S4SvJaeC3HC57BL6CBARac1tm1TybRac1tm2TybTgSox2cre1Amc0TgSox2cre1AmcRac1tm2TybRac1tm1Tyb
• abnormal cell migration_Nckap1<Gt(RRQ139)Byg>/Nckap1<Gt(RRQ139)Byg>
  http://metadb.riken.jp/0003091I129P2OlaHsdC3HNckap1GtRRQ139BygNckap1GtRRQ139BygNckap1GtRRQ139Byg
• abnormal extraembryonic endoderm formation_Rac1<tm1Tyb>/Rac1<tm2Tyb>,Tg(Ttr-cre)1Hadj/0
  http://metadb.riken.jp/0001724I129S4SvJaeC3HC57BL6CBAJRac1tm1TybRac1tm2TybTgTtrcre1Hadj0Rac1tm2TybRac1tm1TybTgTtrcre1Hadj