decreased embryo size_Cops6<Gt(RRI087)Byg>/Cops6<Gt(RRI087)Byg>,Trp53<tm1Glo>/Trp53<tm1Glo>

http://metadb.riken.jp/0001698I129P2OlaHsd129S7SvEvBrdC57BL6JCops6GtRRI087BygCops6GtRRI087BygTrp53tm1GloTrp53tm1GloTrp53tm1GloCops6GtRRI087Byg

decreased embryo size_Cops6<Gt(RRI087)Byg>/Cops6<Gt(RRI087)Byg>,Trp53<tm1Glo>/Trp53<tm1Glo>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• COP9 signalosome subunit 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1349439
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cops6<Gt(RRI087)Byg>/Cops6<Gt(RRI087)Byg>,Trp53<tm1Glo>/Trp53<tm1Glo>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Glo>|Cops6<Gt(RRI087)Byg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased embryo size
  http://purl.obolibrary.org/obo/MP_0001698

文献

http://purl.org/net/cito/citesAsAuthority

• Ruiying. Zhao, et.al., Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/21317535