decreased brown adipose tissue amount_Ptpn11<tm1.1Ics>/Ptpn11<+>

http://metadb.riken.jp/0001780I129S2SvPasC57BL6FVBNPtpn11tm11IcsPtpn11Ptpn11tm11IcsPtpn11

decreased brown adipose tissue amount_Ptpn11<tm1.1Ics>/Ptpn11<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein tyrosine phosphatase, non-receptor type 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:99511

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptpn11<tm1.1Ics>/Ptpn11<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptpn11<tm1.1Ics>|Ptpn11<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased brown adipose tissue amount
  http://purl.obolibrary.org/obo/MP_0001780

文献

http://purl.org/net/cito/citesAsAuthority

• Mylène. Tajan, et.al., LEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesity., Proceedings of the National Academy of Sciences of the United States of America, 2014, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/25288766