decreased IgM level_Tg(IghelMD4)4Ccg/0,Tg(ML5sHEL)5Ccg/0

http://metadb.riken.jp/0001806C57BL6TgIghelMD44CcgTgML5sHEL5CcgTgIghelMD44Ccg0TgML5sHEL5Ccg0TgIghelMD44CcgTgML5sHEL5Ccg

decreased IgM level_Tg(IghelMD4)4Ccg/0,Tg(ML5sHEL)5Ccg/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, Christopher C Goodnow
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053866
• transgene insertion 4, Christopher C Goodnow
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(IghelMD4)4Ccg/0,Tg(ML5sHEL)5Ccg/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(IghelMD4)4Ccg|Tg(ML5sHEL)5Ccg

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• C57BL/6-Tg(IghelMD4)4Ccg Tg(ML5sHEL)5Ccg

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased IgM level
  http://purl.obolibrary.org/obo/MP_0001806

文献

http://purl.org/net/cito/citesAsAuthority

• Pablo A. Silveira, et.al., B cell selection defects underlie the development of diabetogenic APCs in nonobese diabetic mice., Journal of immunology (Baltimore, Md. : 1950), 2004, 172
  http://rdf.ncbi.nlm.nih.gov/pubmed/15067092
• C C. Goodnow, et.al., Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice., Nature, 1988, 334
  http://rdf.ncbi.nlm.nih.gov/pubmed/3261841