C C. Goodnow, et.al., Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice., Nature, 1988, 334

http://rdf.ncbi.nlm.nih.gov/pubmed/3261841

C C. Goodnow, et.al., Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice., Nature, 1988, 334

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(ML5sHEL)5Ccg
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384160
• Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384162
• Tg(ML4sHEL)4Ccg
  http://metadb.riken.jp/db/mgi_rdf/MGI:4889214

class

http://purl.org/net/cito/citesAsAuthority

• Tg(ML5sHEL)5Ccg
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384160
• Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384162
• Tg(ML4sHEL)4Ccg
  http://metadb.riken.jp/db/mgi_rdf/MGI:4889214

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased immature B cell number_Tg(IghelMD4)4Ccg/0
  http://metadb.riken.jp/0008214C57BL6TgIghelMD44CcgTgIghelMD44Ccg0TgIghelMD44Ccg
• abnormal T cell anergy_Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0008747IC57BL6JSfdCBATgML5sHEL5Ccg0TgML5sHEL5Ccg
• abnormal B cell anergy_Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0008744C57BL6TgML5sHEL5CcgTgML5sHEL5Ccg0TgML5sHEL5Ccg
• abnormal B cell anergy_Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0008744IC57BL6JSfdCBATgML5sHEL5Ccg0TgML5sHEL5Ccg
• abnormal circulating protein level_Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0005416C57BL6TgML5sHEL5CcgTgML5sHEL5Ccg0TgML5sHEL5Ccg
• abnormal B cell anergy_Tg(IghelMD4)4Ccg/0,Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0008744C57BL6TgIghelMD44CcgTgML5sHEL5CcgTgIghelMD44Ccg0TgML5sHEL5Ccg0TgIghelMD44CcgTgML5sHEL5Ccg
• increased IgM level_Tg(IghelMD4)4Ccg/0
  http://metadb.riken.jp/0002494C57BL6TgIghelMD44CcgTgIghelMD44Ccg0TgIghelMD44Ccg
• abnormal B cell morphology_Tg(IghelMD4)4Ccg/0
  http://metadb.riken.jp/0004939C57BL6TgIghelMD44CcgTgIghelMD44Ccg0TgIghelMD44Ccg
• decreased IgM level_Tg(IghelMD4)4Ccg/0,Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0001806C57BL6TgIghelMD44CcgTgML5sHEL5CcgTgIghelMD44Ccg0TgML5sHEL5Ccg0TgIghelMD44CcgTgML5sHEL5Ccg