decreased IgM level_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>

http://metadb.riken.jp/0001806I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm

decreased IgM level_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Bruton agammaglobulinemia tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:88216
• tec protein tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:98662

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Btk<tm1Wk>|Tec<tm1Welm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased IgM level
  http://purl.obolibrary.org/obo/MP_0001806

文献

http://purl.org/net/cito/citesAsAuthority

• W. Ellmeier, et.al., Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk., The Journal of experimental medicine, 2000, 192
  http://rdf.ncbi.nlm.nih.gov/pubmed/11104803