W. Ellmeier, et.al., Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk., The Journal of experimental medicine, 2000, 192

http://rdf.ncbi.nlm.nih.gov/pubmed/11104803

W. Ellmeier, et.al., Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk., The Journal of experimental medicine, 2000, 192

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tec<tm1Welm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450883

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased immunoglobulin level_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>
  http://metadb.riken.jp/0002460I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm
• increased pre-B cell number_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>
  http://metadb.riken.jp/0003132I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm
• abnormal humoral immune response_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>
  http://metadb.riken.jp/0001800I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm
• decreased B cell proliferation_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>
  http://metadb.riken.jp/0005093I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm
• decreased IgG2a level_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>
  http://metadb.riken.jp/0008496I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm
• decreased B cell number_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>
  http://metadb.riken.jp/0005017I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm
• decreased IgM level_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>
  http://metadb.riken.jp/0001806I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm
• abnormal spleen marginal zone morphology_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>
  http://metadb.riken.jp/0002362I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm
• decreased IgG3 level_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>
  http://metadb.riken.jp/0008498I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm
• abnormal spleen white pulp morphology_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>
  http://metadb.riken.jp/0002357I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm
• abnormal B cell differentiation_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>
  http://metadb.riken.jp/0002144I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm
• abnormal spleen morphology_Btk<tm1Wk>/Btk<tm1Wk>,Tec<tm1Welm>/Tec<tm1Welm>
  http://metadb.riken.jp/0000689I129P2OlaHsdC57BL6Btktm1WkBtktm1WkTectm1WelmTectm1WelmBtktm1WkTectm1Welm

class

http://purl.org/net/cito/citesAsAuthority

• Tec<tm1Welm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450883