abnormal T cell activation_Drosha<tm1Litt>/Drosha<tm1.1Litt>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<tm4(YFP/icre)Ayr>

http://metadb.riken.jp/0001828I129S1Sv129X1SvJC57BL6FVBNDroshatm1LittDroshatm11LittFoxp3tm4YFPicreAyrFoxp3tm4YFPicreAyrFoxp3tm4YFPicreAyrDroshatm1LittDroshatm11Litt

abnormal T cell activation_Drosha<tm1Litt>/Drosha<tm1.1Litt>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<tm4(YFP/icre)Ayr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• forkhead box P3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891436
• drosha, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:1261425

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Drosha<tm1Litt>/Drosha<tm1.1Litt>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<tm4(YFP/icre)Ayr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Foxp3<tm4(YFP/icre)Ayr>|Drosha<tm1Litt>|Drosha<tm1.1Litt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell activation
  http://purl.obolibrary.org/obo/MP_0001828

文献

http://purl.org/net/cito/citesAsAuthority

• Mark M W. Chong, et.al., The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease., The Journal of experimental medicine, 2008, 205
  http://rdf.ncbi.nlm.nih.gov/pubmed/18725527