abnormal T cell activation_Ctla4<tm1All>/Ctla4<tm1All>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(TcrAND)53Hed/0

http://metadb.riken.jp/0001828I129SSv129X1SvJC57BL6SJLCtla4tm1AllCtla4tm1AllRag1tm1MomRag1tm1MomTgTcrAND53Hed0TgTcrAND53HedRag1tm1MomCtla4tm1All

abnormal T cell activation_Ctla4<tm1All>/Ctla4<tm1All>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(TcrAND)53Hed/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 53, Stephen M Hedrick
  http://metadb.riken.jp/db/mgi_rdf/MGI:3054631
• cytotoxic T-lymphocyte-associated protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88556
• recombination activating gene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97848

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctla4<tm1All>/Ctla4<tm1All>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(TcrAND)53Hed/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcrAND)53Hed|Rag1<tm1Mom>|Ctla4<tm1All>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell activation
  http://purl.obolibrary.org/obo/MP_0001828

文献

http://purl.org/net/cito/citesAsAuthority

• C A. Chambers, et.al., Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4(+) T cell responses., Proceedings of the National Academy of Sciences of the United States of America, 1999, 96
  http://rdf.ncbi.nlm.nih.gov/pubmed/10411922