brain inflammation_H2<dlAb1-Ea>/H2<dlAb1-Ea>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0,Tg(TRATL3A6,TRBTL3A6)#Kito/0

http://metadb.riken.jp/0001847I129S2SvPas129S7SvEvBrdC57BL6H2dlAb1EaH2dlAb1EaRag1tm1MomRag1tm1MomTgHLADRAHLADRB50101hiKito0TgTRATL3A6TRBTL3A6Kito0TgTRATL3A6TRBTL3A6KitoTgHLADRAHLADRB50101hiKitoRag1tm1MomH2dlAb1Ea

brain inflammation_H2<dlAb1-Ea>/H2<dlAb1-Ea>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0,Tg(TRATL3A6,TRBTL3A6)#Kito/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Kouichi Ito
  http://metadb.riken.jp/db/mgi_rdf/MGI:5635433
• recombination activating gene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97848
• transgene insertion hi, Kouichi Ito
  http://metadb.riken.jp/db/mgi_rdf/MGI:5635423
• histocompatibility-2, MHC
  http://metadb.riken.jp/db/mgi_rdf/MGI:95894

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• H2<dlAb1-Ea>/H2<dlAb1-Ea>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0,Tg(TRATL3A6,TRBTL3A6)#Kito/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TRATL3A6,TRBTL3A6)#Kito|Tg(HLA-DRA,HLA-DRB5*0101)hiKito|Rag1<tm1Mom>|H2<dlAb1-Ea>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• brain inflammation
  http://purl.obolibrary.org/obo/MP_0001847

文献

http://purl.org/net/cito/citesAsAuthority

• Jacqueline A. Quandt, et.al., Myelin basic protein-specific TCR/HLA-DRB5*01:01 transgenic mice support the etiologic role of DRB5*01:01 in multiple sclerosis., Journal of immunology (Baltimore, Md. : 1950), 2012, 189
  http://rdf.ncbi.nlm.nih.gov/pubmed/22888134