increased mammary adenocarcinoma incidence_Brca1<tm1Bhk>/Brca1<+>,Cdkn2c<tm1Yxi>/Cdkn2c<tm1Yxi>

http://metadb.riken.jp/0001883C129Cdkn2ctm1YxiBrca1tm1BhkBrca1tm1BhkBrca1Cdkn2ctm1YxiCdkn2ctm1YxiCdkn2ctm1YxiBrca1tm1BhkBrca1

increased mammary adenocarcinoma incidence_Brca1<tm1Bhk>/Brca1<+>,Cdkn2c<tm1Yxi>/Cdkn2c<tm1Yxi>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• breast cancer 1, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:104537
• cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  http://metadb.riken.jp/db/mgi_rdf/MGI:105388

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca1<tm1Bhk>/Brca1<+>,Cdkn2c<tm1Yxi>/Cdkn2c<tm1Yxi>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2c<tm1Yxi>|Brca1<tm1Bhk>|Brca1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• C.129-Cdkn2c<tm1Yxi> Brca1<tm1Bhk>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0001883

文献

http://purl.org/net/cito/citesAsAuthority

• F. Bai, et.al., Germline mutation of Brca1 alters the fate of mammary luminal cells and causes luminal-to-basal mammary tumor transformation., Oncogene, 2013, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/22777348