increased mammary adenocarcinoma incidence_Gt(ROSA)26Sor<tm1(CAG-PIK3CA*H1047R,-EGFP)Balj>/Gt(ROSA)26Sor<+>,Tg(MMTV-cre)7Mul/0

http://metadb.riken.jp/0001883IBALBcFVBNGtROSA26Sortm1CAGPIK3CAH1047REGFPBaljGtROSA26SorTgMMTVcre7Mul0GtROSA26Sortm1CAGPIK3CAH1047REGFPBaljGtROSA26SorTgMMTVcre7Mul

increased mammary adenocarcinoma incidence_Gt(ROSA)26Sor<tm1(CAG-PIK3CA*H1047R,-EGFP)Balj>/Gt(ROSA)26Sor<+>,Tg(MMTV-cre)7Mul/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 7, William J Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:3589277

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(CAG-PIK3CA*H1047R,-EGFP)Balj>/Gt(ROSA)26Sor<+>,Tg(MMTV-cre)7Mul/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(CAG-PIK3CA*H1047R,-EGFP)Balj>|Gt(ROSA)26Sor<+>|Tg(MMTV-cre)7Mul

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0001883

文献

http://purl.org/net/cito/citesAsAuthority

• Dominique S. Meyer, et.al., Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heterogeneous tumors., Cancer research, 2011, 71
  http://rdf.ncbi.nlm.nih.gov/pubmed/21482677