Dominique S. Meyer, et.al., Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heterogeneous tumors., Cancer research, 2011, 71

http://rdf.ncbi.nlm.nih.gov/pubmed/21482677

Dominique S. Meyer, et.al., Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heterogeneous tumors., Cancer research, 2011, 71

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(CAG-PIK3CA*H1047R,-EGFP)Balj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5052133

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased mammary adenocarcinoma incidence_Gt(ROSA)26Sor<tm1(CAG-PIK3CA*H1047R,-EGFP)Balj>/Gt(ROSA)26Sor<+>,Tg(Wap-cre)1Gsc/0
  http://metadb.riken.jp/0001883IBALBcC57BL6FVBNGtROSA26Sortm1CAGPIK3CAH1047REGFPBaljGtROSA26SorTgWapcre1Gsc0GtROSA26SorTgWapcre1GscGtROSA26Sortm1CAGPIK3CAH1047REGFPBalj
• abnormal involution of the mammary gland_Gt(ROSA)26Sor<tm1(CAG-PIK3CA*H1047R,-EGFP)Balj>/Gt(ROSA)26Sor<+>,Tg(Wap-cre)1Gsc/0
  http://metadb.riken.jp/0006271IBALBcC57BL6FVBNGtROSA26Sortm1CAGPIK3CAH1047REGFPBaljGtROSA26SorTgWapcre1Gsc0GtROSA26SorTgWapcre1GscGtROSA26Sortm1CAGPIK3CAH1047REGFPBalj
• premature death_Gt(ROSA)26Sor<tm1(CAG-PIK3CA*H1047R,-EGFP)Balj>/Gt(ROSA)26Sor<+>,Tg(MMTV-cre)7Mul/0
  http://metadb.riken.jp/0002083IBALBcFVBNGtROSA26Sortm1CAGPIK3CAH1047REGFPBaljGtROSA26SorTgMMTVcre7Mul0GtROSA26Sortm1CAGPIK3CAH1047REGFPBaljGtROSA26SorTgMMTVcre7Mul
• increased mammary adenocarcinoma incidence_Gt(ROSA)26Sor<tm1(CAG-PIK3CA*H1047R,-EGFP)Balj>/Gt(ROSA)26Sor<+>,Tg(MMTV-cre)7Mul/0
  http://metadb.riken.jp/0001883IBALBcFVBNGtROSA26Sortm1CAGPIK3CAH1047REGFPBaljGtROSA26SorTgMMTVcre7Mul0GtROSA26Sortm1CAGPIK3CAH1047REGFPBaljGtROSA26SorTgMMTVcre7Mul
• increased mammary gland tumor incidence_Gt(ROSA)26Sor<tm1(CAG-PIK3CA*H1047R,-EGFP)Balj>/Gt(ROSA)26Sor<+>,Tg(Wap-cre)1Gsc/0
  http://metadb.riken.jp/0010299IBALBcC57BL6FVBNGtROSA26Sortm1CAGPIK3CAH1047REGFPBaljGtROSA26SorTgWapcre1Gsc0GtROSA26SorTgWapcre1GscGtROSA26Sortm1CAGPIK3CAH1047REGFPBalj

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(CAG-PIK3CA*H1047R,-EGFP)Balj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5052133