increased mammary adenocarcinoma incidence_Dock1<tm2.1Jfco>/Dock1<+>,Tg(MMTV-Erbb2*,-cre)1Mul/0

http://metadb.riken.jp/0001883IC57BL6FVBNJDock1tm21JfcoDock1TgMMTVErbb2cre1Mul0Dock1TgMMTVErbb2cre1MulDock1tm21Jfco

increased mammary adenocarcinoma incidence_Dock1<tm2.1Jfco>/Dock1<+>,Tg(MMTV-Erbb2*,-cre)1Mul/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, William J Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361015
• dedicator of cytokinesis 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2429765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dock1<tm2.1Jfco>/Dock1<+>,Tg(MMTV-Erbb2*,-cre)1Mul/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dock1<+>|Tg(MMTV-Erbb2*,-cre)1Mul|Dock1<tm2.1Jfco>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * FVB/NJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0001883

文献

http://purl.org/net/cito/citesAsAuthority

• Mélanie. Laurin, et.al., Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/23592719