Mélanie. Laurin, et.al., Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

http://rdf.ncbi.nlm.nih.gov/pubmed/23592719

Mélanie. Laurin, et.al., Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Dock1<tm2.1Jfco>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5515752

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased tumor latency_Dock1<tm2.1Jfco>/Dock1<+>,Tg(MMTV-Erbb2*,-cre)1Mul/0
  http://metadb.riken.jp/0009828IC57BL6FVBNJDock1tm21JfcoDock1TgMMTVErbb2cre1Mul0Dock1TgMMTVErbb2cre1MulDock1tm21Jfco
• decreased metastatic potential_Dock1<tm2.1Jfco>/Dock1<tm2.1Jfco>,Tg(MMTV-Erbb2*,-cre)1Mul/0
  http://metadb.riken.jp/0001273IC57BL6FVBNJDock1tm21JfcoDock1tm21JfcoTgMMTVErbb2cre1Mul0Dock1tm21JfcoTgMMTVErbb2cre1Mul
• increased mammary adenocarcinoma incidence_Dock1<tm2.1Jfco>/Dock1<tm2.1Jfco>,Tg(MMTV-Erbb2*,-cre)1Mul/0
  http://metadb.riken.jp/0001883IC57BL6FVBNJDock1tm21JfcoDock1tm21JfcoTgMMTVErbb2cre1Mul0Dock1tm21JfcoTgMMTVErbb2cre1Mul
• decreased cell proliferation_Dock1<tm2.1Jfco>/Dock1<tm2.1Jfco>,Tg(MMTV-Erbb2*,-cre)1Mul/0
  http://metadb.riken.jp/0000352IC57BL6FVBNJDock1tm21JfcoDock1tm21JfcoTgMMTVErbb2cre1Mul0Dock1tm21JfcoTgMMTVErbb2cre1Mul
• decreased tumor growth/size_Dock1<tm2.1Jfco>/Dock1<tm2.1Jfco>,Tg(MMTV-Erbb2*,-cre)1Mul/0
  http://metadb.riken.jp/0003447IC57BL6FVBNJDock1tm21JfcoDock1tm21JfcoTgMMTVErbb2cre1Mul0Dock1tm21JfcoTgMMTVErbb2cre1Mul
• increased mammary gland tumor incidence_Dock1<tm2.1Jfco>/Dock1<tm2.1Jfco>,Tg(MMTV-Erbb2*,-cre)1Mul/0
  http://metadb.riken.jp/0010299IC57BL6FVBNJDock1tm21JfcoDock1tm21JfcoTgMMTVErbb2cre1Mul0Dock1tm21JfcoTgMMTVErbb2cre1Mul
• increased mammary gland tumor incidence_Dock1<tm2.1Jfco>/Dock1<+>,Tg(MMTV-Erbb2*,-cre)1Mul/0
  http://metadb.riken.jp/0010299IC57BL6FVBNJDock1tm21JfcoDock1TgMMTVErbb2cre1Mul0Dock1TgMMTVErbb2cre1MulDock1tm21Jfco
• increased apoptosis_Dock1<tm2.1Jfco>/Dock1<tm2.1Jfco>,Tg(MMTV-Erbb2*,-cre)1Mul/0
  http://metadb.riken.jp/0006042IC57BL6FVBNJDock1tm21JfcoDock1tm21JfcoTgMMTVErbb2cre1Mul0Dock1tm21JfcoTgMMTVErbb2cre1Mul
• increased tumor latency_Dock1<tm2.1Jfco>/Dock1<tm2.1Jfco>,Tg(MMTV-Erbb2*,-cre)1Mul/0
  http://metadb.riken.jp/0009828IC57BL6FVBNJDock1tm21JfcoDock1tm21JfcoTgMMTVErbb2cre1Mul0Dock1tm21JfcoTgMMTVErbb2cre1Mul
• increased mammary adenocarcinoma incidence_Dock1<tm2.1Jfco>/Dock1<+>,Tg(MMTV-Erbb2*,-cre)1Mul/0
  http://metadb.riken.jp/0001883IC57BL6FVBNJDock1tm21JfcoDock1TgMMTVErbb2cre1Mul0Dock1TgMMTVErbb2cre1MulDock1tm21Jfco

class

http://purl.org/net/cito/citesAsAuthority

• Dock1<tm2.1Jfco>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5515752