impaired synaptic plasticity_Tg(Prnp-MAPT*K274Q*K281Q)1Lgn/0

http://metadb.riken.jp/0001900IC57BL6FVBNTgPrnpMAPTK274QK281Q1Lgn0TgPrnpMAPTK274QK281Q1Lgn

impaired synaptic plasticity_Tg(Prnp-MAPT*K274Q*K281Q)1Lgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Li Gan
  http://metadb.riken.jp/db/mgi_rdf/MGI:5810412

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Prnp-MAPT*K274Q*K281Q)1Lgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp-MAPT*K274Q*K281Q)1Lgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired synaptic plasticity
  http://purl.obolibrary.org/obo/MP_0001900

文献

http://purl.org/net/cito/citesAsAuthority

• Tara E. Tracy, et.al., Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss., Neuron, 2016, 90
  http://rdf.ncbi.nlm.nih.gov/pubmed/27041503