Tara E. Tracy, et.al., Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss., Neuron, 2016, 90

http://rdf.ncbi.nlm.nih.gov/pubmed/27041503

Tara E. Tracy, et.al., Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss., Neuron, 2016, 90

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-MAPT)#Lgn
  http://metadb.riken.jp/db/mgi_rdf/MGI:5708386
• Tg(Prnp-MAPT*K274Q*K281Q)1Lgn
  http://metadb.riken.jp/db/mgi_rdf/MGI:5708387
• Tg(Prnp-MAPT*K274Q*K281Q)286Lgn
  http://metadb.riken.jp/db/mgi_rdf/MGI:5708388

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal dentate gyrus morphology_Tg(Prnp-MAPT*K274Q*K281Q)286Lgn/0
  http://metadb.riken.jp/0000812IC57BL6FVBNTgPrnpMAPTK274QK281Q286Lgn0TgPrnpMAPTK274QK281Q286Lgn
• reduced long term potentiation_Tg(Prnp-MAPT*K274Q*K281Q)1Lgn/0
  http://metadb.riken.jp/0001473IC57BL6FVBNTgPrnpMAPTK274QK281Q1Lgn0TgPrnpMAPTK274QK281Q1Lgn
• reduced long term potentiation_Tg(Prnp-MAPT*K274Q*K281Q)286Lgn/0
  http://metadb.riken.jp/0001473IC57BL6FVBNTgPrnpMAPTK274QK281Q286Lgn0TgPrnpMAPTK274QK281Q286Lgn
• impaired synaptic plasticity_Tg(Prnp-MAPT*K274Q*K281Q)1Lgn/0
  http://metadb.riken.jp/0001900IC57BL6FVBNTgPrnpMAPTK274QK281Q1Lgn0TgPrnpMAPTK274QK281Q1Lgn
• impaired synaptic plasticity_Tg(Prnp-MAPT*K274Q*K281Q)286Lgn/0
  http://metadb.riken.jp/0001900IC57BL6FVBNTgPrnpMAPTK274QK281Q286Lgn0TgPrnpMAPTK274QK281Q286Lgn
• abnormal excitatory postsynaptic potential_Tg(Prnp-MAPT*K274Q*K281Q)286Lgn/0
  http://metadb.riken.jp/0002912IC57BL6FVBNTgPrnpMAPTK274QK281Q286Lgn0TgPrnpMAPTK274QK281Q286Lgn
他8件を見る
• astrocytosis_Tg(Prnp-MAPT*K274Q*K281Q)1Lgn/0
  http://metadb.riken.jp/0003354IC57BL6FVBNTgPrnpMAPTK274QK281Q1Lgn0TgPrnpMAPTK274QK281Q1Lgn
• astrocytosis_Tg(Prnp-MAPT*K274Q*K281Q)286Lgn/0
  http://metadb.riken.jp/0003354IC57BL6FVBNTgPrnpMAPTK274QK281Q286Lgn0TgPrnpMAPTK274QK281Q286Lgn
• astrocytosis_Tg(Prnp-MAPT)#Lgn/0
  http://metadb.riken.jp/0003354IC57BL6FVBNTgPrnpMAPTLgn0TgPrnpMAPTLgn
• tau protein deposits_Tg(Prnp-MAPT*K274Q*K281Q)1Lgn/0
  http://metadb.riken.jp/0004250IC57BL6FVBNTgPrnpMAPTK274QK281Q1Lgn0TgPrnpMAPTK274QK281Q1Lgn
• tau protein deposits_Tg(Prnp-MAPT*K274Q*K281Q)286Lgn/0
  http://metadb.riken.jp/0004250IC57BL6FVBNTgPrnpMAPTK274QK281Q286Lgn0TgPrnpMAPTK274QK281Q286Lgn
• abnormal long term spatial reference memory_Tg(Prnp-MAPT*K274Q*K281Q)286Lgn/0
  http://metadb.riken.jp/0008432IC57BL6FVBNTgPrnpMAPTK274QK281Q286Lgn0TgPrnpMAPTK274QK281Q286Lgn
• impaired contextual conditioning behavior_Tg(Prnp-MAPT*K274Q*K281Q)286Lgn/0
  http://metadb.riken.jp/0009454IC57BL6FVBNTgPrnpMAPTK274QK281Q286Lgn0TgPrnpMAPTK274QK281Q286Lgn
• impaired discrimination learning_Tg(Prnp-MAPT*K274Q*K281Q)286Lgn/0
  http://metadb.riken.jp/0012296IC57BL6FVBNTgPrnpMAPTK274QK281Q286Lgn0TgPrnpMAPTK274QK281Q286Lgn

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-MAPT)#Lgn
  http://metadb.riken.jp/db/mgi_rdf/MGI:5708386
• Tg(Prnp-MAPT*K274Q*K281Q)1Lgn
  http://metadb.riken.jp/db/mgi_rdf/MGI:5708387
• Tg(Prnp-MAPT*K274Q*K281Q)286Lgn
  http://metadb.riken.jp/db/mgi_rdf/MGI:5708388