increased tumor incidence_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>

http://metadb.riken.jp/0002020I129P2OlaHsdC3HeBFeJC57BL6JMcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm6GtYHD248BygMcm6Mcm6Mcm3GtRRR002BygMcm3Mcm4chaos3Mcm6GtYHD248Byg

increased tumor incidence_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• minichromosome maintenance complex component 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1298227
• minichromosome maintenance complex component 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:103199
• minichromosome maintenance complex component 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:101845

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mcm6<+>|Mcm3<Gt(RRR002)Byg>|Mcm3<+>|Mcm4<chaos3>|Mcm6<Gt(YHD248)Byg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002020

文献

http://purl.org/net/cito/citesAsAuthority

• Chen-Hua. Chuang, et.al., Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress., PLoS genetics, 2010, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/20838603