Chen-Hua. Chuang, et.al., Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress., PLoS genetics, 2010, 6

http://rdf.ncbi.nlm.nih.gov/pubmed/20838603

Chen-Hua. Chuang, et.al., Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress., PLoS genetics, 2010, 6

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm2Mcm2GtAB0178WtsiMcm3Mcm3GtRRR002Byg
• chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4GtRRE056BygMcm4Mcm6GtYHD248BygMcm6Mcm2GtAB0178WtsiMcm3Mcm3GtRRR002BygMcm6Mcm4GtRRE056BygMcm2Mcm4Mcm6GtYHD248Byg
• chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>,Mcm7<Gt(YTA285)Byg>/Mcm7<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4GtRRE056BygMcm4Mcm6GtYHD248BygMcm6Mcm7GtYTA285BygMcm7Mcm4Mcm6GtYHD248BygMcm2Mcm2GtAB0178WtsiMcm7Mcm3Mcm3GtRRR002BygMcm6Mcm4GtRRE056BygMcm7GtYTA285Byg
• perinatal lethality, incomplete penetrance_Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0011090I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4GtRRE056BygMcm4chaos3Mcm4GtRRE056Byg
• increased mammary gland tumor incidence_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0010299I129P2OlaHsdC3HeBFeJC57BL6JMcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm3Mcm3GtRRR002BygMcm4chaos3
• decreased fibroblast proliferation_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0011704I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm4chaos3Mcm4chaos3Mcm2GtAB0178WtsiMcm2Mcm4chaos3
• prenatal lethality, incomplete penetrance_Mcm4<chaos3>/Mcm4<chaos3>,Mcm7<Gt(YTA285)Byg>/Mcm7<+>
  http://metadb.riken.jp/0011101I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4chaos3Mcm7GtYTA285BygMcm7Mcm7Mcm7GtYTA285BygMcm4chaos3
• premature death_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002083IC57BL6JMcm4chaos3Mcm4chaos3Mcm4chaos3
• chromosomal instability_Mcm4<Gt(RRE056)Byg>/Mcm4<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm4GtRRE056BygMcm4Mcm4GtRRE056BygMcm4
• chromosomal instability_Mcm3<Gt(RRR002)Byg>/Mcm3<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm3GtRRR002BygMcm3Mcm3Mcm3GtRRR002Byg
• postnatal lethality, incomplete penetrance_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0011086I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm2Mcm4chaos3Mcm3GtRRR002BygMcm3Mcm2GtAB0178Wtsi
• prenatal lethality, complete penetrance_Mcm2<Gt(AB0178)Wtsi>/Mcm2<Gt(AB0178)Wtsi>
  http://metadb.riken.jp/0011091I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2GtAB0178WtsiMcm2GtAB0178Wtsi
• increased tumor incidence_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0002020I129P2OlaHsdC3HeBFeJC57BL6JMcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm6GtYHD248BygMcm6Mcm6Mcm3GtRRR002BygMcm3Mcm4chaos3Mcm6GtYHD248Byg
• chromosomal instability_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm3GtRRR002BygMcm3Mcm4GtRRE056BygMcm4Mcm4Mcm3GtRRR002BygMcm4GtRRE056BygMcm3
• increased lymphoma incidence_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0012431I129P2OlaHsdC3HeBFeJC57BL6JMcm3GtRRR002BygMcm3Mcm4chaos3Mcm4GtRRE056BygMcm3Mcm4GtRRE056BygMcm3GtRRR002BygMcm4chaos3
• abnormal erythrocyte morphology_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002447IC57BL6JMcm4chaos3Mcm4chaos3Mcm4chaos3
• increased lymphoma incidence_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0012431IC57BL6JMcm4chaos3Mcm4chaos3Mcm4chaos3
• abnormal erythrocyte morphology_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm3GtRRR002BygMcm3Mcm4GtRRE056BygMcm4Mcm4Mcm3GtRRR002BygMcm4GtRRE056BygMcm3
• chromosomal instability_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0008866IC57BL6JMcm4chaos3Mcm4chaos3Mcm4chaos3
• abnormal erythrocyte morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>,Mcm7<Gt(YTA285)Byg>/Mcm7<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4GtRRE056BygMcm4Mcm6GtYHD248BygMcm6Mcm7GtYTA285BygMcm7Mcm4Mcm6GtYHD248BygMcm2Mcm2GtAB0178WtsiMcm7Mcm3Mcm3GtRRR002BygMcm6Mcm4GtRRE056BygMcm7GtYTA285Byg
• abnormal erythrocyte morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm4chaos3Mcm4chaos3Mcm2GtAB0178WtsiMcm2Mcm4chaos3
• increased leukemia incidence_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002026I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm4chaos3Mcm4chaos3Mcm2GtAB0178WtsiMcm2Mcm4chaos3
• decreased body weight_Mcm4<chaos3>/Mcm4<chaos3>,Mcm7<Gt(YTA285)Byg>/Mcm7<+>
  http://metadb.riken.jp/0001262I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4chaos3Mcm7GtYTA285BygMcm7Mcm7Mcm7GtYTA285BygMcm4chaos3
• reticulocytosis_Mcm4<chaos3>/Mcm4<chaos3>,Mcm7<Gt(YTA285)Byg>/Mcm7<+>
  http://metadb.riken.jp/0002640I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4chaos3Mcm7GtYTA285BygMcm7Mcm7Mcm7GtYTA285BygMcm4chaos3
• abnormal erythrocyte morphology_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm3GtRRR002BygMcm3Mcm4GtRRE056BygMcm4Mcm6GtYHD248BygMcm6Mcm6GtYHD248BygMcm4Mcm4GtRRE056BygMcm6Mcm3GtRRR002BygMcm3
• postnatal lethality, incomplete penetrance_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0011086I129P2OlaHsdC3HeBFeJC57BL6JMcm3GtRRR002BygMcm3Mcm4chaos3Mcm4GtRRE056BygMcm3Mcm4GtRRE056BygMcm3GtRRR002BygMcm4chaos3
• abnormal erythrocyte morphology_Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm6GtYHD248BygMcm6Mcm6Mcm6GtYHD248Byg
• postnatal lethality, incomplete penetrance_Mcm4<chaos3>/Mcm4<chaos3>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0011086I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4chaos3Mcm6GtYHD248BygMcm6Mcm4chaos3Mcm6GtYHD248BygMcm6
• abnormal erythrocyte morphology_Mcm3<Gt(RRR002)Byg>/Mcm3<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm3GtRRR002BygMcm3Mcm3Mcm3GtRRR002Byg
• chromosomal instability_Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm6GtYHD248BygMcm6Mcm6Mcm6GtYHD248Byg
• decreased body weight_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0001262I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm4chaos3Mcm4chaos3Mcm2GtAB0178WtsiMcm2Mcm4chaos3
• chromosomal instability_Mcm4<chaos3>/Mcm4<chaos3>,Mcm7<Gt(YTA285)Byg>/Mcm7<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4chaos3Mcm7GtYTA285BygMcm7Mcm7Mcm7GtYTA285BygMcm4chaos3
• increased mammary gland tumor incidence_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0010299IC57BL6JMcm4chaos3Mcm4chaos3Mcm4chaos3
• abnormal erythrocyte morphology_Mcm4<Gt(RRE056)Byg>/Mcm4<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm4GtRRE056BygMcm4Mcm4GtRRE056BygMcm4
• abnormal erythrocyte morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm2Mcm2GtAB0178WtsiMcm3Mcm3GtRRR002Byg
• chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm6GtYHD248BygMcm6Mcm6Mcm3GtRRR002BygMcm2GtAB0178WtsiMcm3Mcm2Mcm6GtYHD248Byg
• increased T cell derived lymphoma incidence_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002024I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm4chaos3Mcm4chaos3Mcm2GtAB0178WtsiMcm2Mcm4chaos3
• postnatal lethality, incomplete penetrance_Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0011086I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4GtRRE056BygMcm4chaos3Mcm4GtRRE056Byg
• increased tumor incidence_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002020I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm2Mcm4chaos3Mcm3GtRRR002BygMcm3Mcm2GtAB0178Wtsi
• decreased body weight_Mcm4<chaos3>/Mcm4<chaos3>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0001262I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4chaos3Mcm6GtYHD248BygMcm6Mcm4chaos3Mcm6GtYHD248BygMcm6
• decreased fibroblast proliferation_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0011704I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm2Mcm4chaos3Mcm3GtRRR002BygMcm3Mcm2GtAB0178Wtsi
• abnormal erythrocyte morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm6GtYHD248BygMcm6Mcm6Mcm3GtRRR002BygMcm2GtAB0178WtsiMcm3Mcm2Mcm6GtYHD248Byg
• abnormal erythrocyte morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm2Mcm4chaos3Mcm3GtRRR002BygMcm3Mcm2GtAB0178Wtsi
• increased tumor incidence_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002020I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm4chaos3Mcm4chaos3Mcm2GtAB0178WtsiMcm2Mcm4chaos3
• chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm4GtRRE056BygMcm4Mcm4GtRRE056BygMcm2GtAB0178WtsiMcm4Mcm2
• abnormal erythrocyte morphology_Mcm4<chaos3>/Mcm4<chaos3>,Mcm7<Gt(YTA285)Byg>/Mcm7<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4chaos3Mcm7GtYTA285BygMcm7Mcm7Mcm7GtYTA285BygMcm4chaos3
• prenatal lethality, incomplete penetrance_Mcm4<chaos3>/Mcm4<chaos3>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0011101I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4chaos3Mcm6GtYHD248BygMcm6Mcm4chaos3Mcm6GtYHD248BygMcm6
• chromosomal instability_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm3GtRRR002BygMcm3Mcm4GtRRE056BygMcm4Mcm6GtYHD248BygMcm6Mcm6GtYHD248BygMcm4Mcm4GtRRE056BygMcm6Mcm3GtRRR002BygMcm3
• chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm2GtAB0178WtsiMcm2
• chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm4GtRRE056BygMcm4Mcm6GtYHD248BygMcm6Mcm6GtYHD248BygMcm4Mcm2Mcm4GtRRE056BygMcm6Mcm2GtAB0178Wtsi
• abnormal erythrocyte morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4GtRRE056BygMcm4Mcm6GtYHD248BygMcm6Mcm2GtAB0178WtsiMcm3Mcm3GtRRR002BygMcm6Mcm4GtRRE056BygMcm2Mcm4Mcm6GtYHD248Byg
• chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm4chaos3Mcm4chaos3Mcm2GtAB0178WtsiMcm2Mcm4chaos3
• chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm2Mcm4chaos3Mcm3GtRRR002BygMcm3Mcm2GtAB0178Wtsi
• abnormal erythrocyte morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm2GtAB0178WtsiMcm2
• prenatal lethality, complete penetrance_Mcm7<Gt(YTA285)Byg>/Mcm7<Gt(YTA285)Byg>
  http://metadb.riken.jp/0011091I129P2OlaHsdC3HeBFeJMcm7GtYTA285BygMcm7GtYTA285BygMcm7GtYTA285Byg
• abnormal erythrocyte morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4GtRRE056BygMcm4Mcm4Mcm2Mcm3Mcm2GtAB0178WtsiMcm4GtRRE056BygMcm3GtRRR002Byg
• abnormal erythrocyte morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm4GtRRE056BygMcm4Mcm6GtYHD248BygMcm6Mcm6GtYHD248BygMcm4Mcm2Mcm4GtRRE056BygMcm6Mcm2GtAB0178Wtsi
• chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4GtRRE056BygMcm4Mcm4Mcm2Mcm3Mcm2GtAB0178WtsiMcm4GtRRE056BygMcm3GtRRR002Byg
• prenatal lethality, complete penetrance_Mcm3<Gt(RRR002)Byg>/Mcm3<Gt(RRR002)Byg>
  http://metadb.riken.jp/0011091I129P2OlaHsdC3HeBFeJMcm3GtRRR002BygMcm3GtRRR002BygMcm3GtRRR002Byg
• increased lymphoma incidence_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0012431I129P2OlaHsdC3HeBFeJC57BL6JMcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm6GtYHD248BygMcm6Mcm6Mcm3GtRRR002BygMcm3Mcm4chaos3Mcm6GtYHD248Byg
• abnormal erythrocyte morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>,Mcm7<Gt(YTA285)Byg>/Mcm7<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm6GtYHD248BygMcm6Mcm7GtYTA285BygMcm7Mcm7Mcm3Mcm2GtAB0178WtsiMcm3GtRRR002BygMcm6Mcm7GtYTA285BygMcm6GtYHD248BygMcm2
• premature death_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002083I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm4chaos3Mcm4chaos3Mcm2GtAB0178WtsiMcm2Mcm4chaos3
• abnormal erythrocyte morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<Gt(RRE056)Byg>/Mcm4<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm4GtRRE056BygMcm4Mcm4GtRRE056BygMcm2GtAB0178WtsiMcm4Mcm2
• chromosomal instability_Mcm7<Gt(YTA285)Byg>/Mcm7<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm7GtYTA285BygMcm7Mcm7Mcm7GtYTA285Byg
• increased T cell derived lymphoma incidence_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002024IC57BL6JMcm4chaos3Mcm4chaos3Mcm4chaos3
• postnatal lethality, incomplete penetrance_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>
  http://metadb.riken.jp/0011086I129P2OlaHsdC3HeBFeJC57BL6JMcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm6GtYHD248BygMcm6Mcm6Mcm3GtRRR002BygMcm3Mcm4chaos3Mcm6GtYHD248Byg
• increased mammary gland tumor incidence_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0010299I129P2OlaHsdC3HeBFeJC57BL6JMcm3GtRRR002BygMcm3Mcm4chaos3Mcm4GtRRE056BygMcm3Mcm4GtRRE056BygMcm3GtRRR002BygMcm4chaos3
• abnormal pluripotent precursor cell morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002399I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm2Mcm4chaos3Mcm3GtRRR002BygMcm3Mcm2GtAB0178Wtsi
• abnormal pluripotent precursor cell morphology_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002399I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm4chaos3Mcm4chaos3Mcm2GtAB0178WtsiMcm2Mcm4chaos3
• prenatal lethality, complete penetrance_Mcm6<Gt(YHD248)Byg>/Mcm6<Gt(YHD248)Byg>
  http://metadb.riken.jp/0011091I129P2OlaHsdC3HeBFeJMcm6GtYHD248BygMcm6GtYHD248BygMcm6GtYHD248Byg
• abnormal erythrocyte morphology_Mcm7<Gt(YTA285)Byg>/Mcm7<+>
  http://metadb.riken.jp/0002447I129P2OlaHsdC3HeBFeJMcm7GtYTA285BygMcm7Mcm7Mcm7GtYTA285Byg
• abnormal pluripotent precursor cell morphology_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002399I129P2OlaHsdC3HeBFeJC57BL6JMcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm3Mcm3GtRRR002BygMcm4chaos3
• postnatal lethality, incomplete penetrance_Mcm4<chaos3>/Mcm4<chaos3>,Mcm7<Gt(YTA285)Byg>/Mcm7<+>
  http://metadb.riken.jp/0011086I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4chaos3Mcm7GtYTA285BygMcm7Mcm7Mcm7GtYTA285BygMcm4chaos3
• premature death_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0002083I129P2OlaHsdC3HeBFeJC57BL6JMcm3GtRRR002BygMcm3Mcm4chaos3Mcm4GtRRE056BygMcm3Mcm4GtRRE056BygMcm3GtRRR002BygMcm4chaos3
• premature death_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002083I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm4chaos3Mcm4chaos3Mcm2Mcm4chaos3Mcm3GtRRR002BygMcm3Mcm2GtAB0178Wtsi
• chromosomal instability_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>,Mcm7<Gt(YTA285)Byg>/Mcm7<+>
  http://metadb.riken.jp/0008866I129P2OlaHsdC3HeBFeJMcm2GtAB0178WtsiMcm2Mcm3GtRRR002BygMcm3Mcm6GtYHD248BygMcm6Mcm7GtYTA285BygMcm7Mcm7Mcm3Mcm2GtAB0178WtsiMcm3GtRRR002BygMcm6Mcm7GtYTA285BygMcm6GtYHD248BygMcm2
• reticulocytosis_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002640I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm4chaos3Mcm4chaos3Mcm2GtAB0178WtsiMcm2Mcm4chaos3
• postnatal lethality_Mcm2<Gt(AB0178)Wtsi>/Mcm2<+>,Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002082I129P2OlaHsdC3HeBFeJC57BL6JMcm2GtAB0178WtsiMcm2Mcm4chaos3Mcm4chaos3Mcm2GtAB0178WtsiMcm2Mcm4chaos3

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD02696
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02696
• CD02694
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02694
• CD02476
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02476
• CD03697
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03697
• CD02706
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02706