increased B cell derived lymphoma incidence_Npm1<tm1Gsva>/Npm1<+>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0002023IC57BL6CBANpm1tm1GsvaNpm1TgMx1cre1Cgn0TgMx1cre1CgnNpm1Npm1tm1Gsva

increased B cell derived lymphoma incidence_Npm1<tm1Gsva>/Npm1<+>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nucleophosmin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:106184
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Npm1<tm1Gsva>/Npm1<+>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Npm1<+>|Npm1<tm1Gsva>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased B cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002023

文献

http://purl.org/net/cito/citesAsAuthority

• George S. Vassiliou, et.al., Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice., Nature genetics, 2011, 43
  http://rdf.ncbi.nlm.nih.gov/pubmed/21441929