increased T cell derived lymphoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>

http://metadb.riken.jp/0002024I129S2SvPasTrp53tm1TyjTrp53tm1TyjTrp53tm1Tyj

increased T cell derived lymphoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Tyj>/Trp53<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell derived lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0002024

文献

http://purl.org/net/cito/citesAsAuthority

• Kenneth P. Olive, et.al., Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome., Cell, 2004, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/15607980
• Jin-Na. Min, et.al., The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability., Cell research, 2013, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/23979016
• Ewa. Sicinska, et.al., Requirement for cyclin D3 in lymphocyte development and T cell leukemias., Cancer cell, 2003, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/14706337