Jin-Na. Min, et.al., The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability., Cell research, 2013, 23

http://rdf.ncbi.nlm.nih.gov/pubmed/23979016

Jin-Na. Min, et.al., The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability., Cell research, 2013, 23

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ino80<tm1Schg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5698824
• Ino80<tm1.1Schg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5698826

class

http://purl.org/net/cito/citesAsAuthority

• Ino80<tm1Schg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5698824
• Ino80<tm1.1Schg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5698826

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002083IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• abnormal DNA replication_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008057IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• abnormal DNA repair_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008058IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• embryonic lethality, incomplete penetrance_Ino80<tm1.1Schg>/Ino80<tm1.1Schg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0011102I129S2SvPasC57BL6JIno80tm11SchgIno80tm11SchgTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjIno80tm11Schg
• decreased body weight_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001262IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• embryonic lethality, incomplete penetrance_Ino80<tm1.1Schg>/Ino80<tm1.1Schg>
  http://metadb.riken.jp/0011102IC57BL6JIno80tm11SchgIno80tm11SchgIno80tm11Schg
• preweaning lethality, complete penetrance_Ino80<tm1.1Schg>/Ino80<tm1.1Schg>
  http://metadb.riken.jp/0011100IC57BL6JIno80tm11SchgIno80tm11SchgIno80tm11Schg
• limb grasping_Ino80<tm1.1Schg>/Ino80<+>
  http://metadb.riken.jp/0001513IC57BL6JIno80tm11SchgIno80Ino80Ino80tm11Schg
• abnormal telomere morphology_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0010207IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• embryonic growth retardation_Ino80<tm1.1Schg>/Ino80<tm1.1Schg>
  http://metadb.riken.jp/0003984IC57BL6JIno80tm11SchgIno80tm11SchgIno80tm11Schg
• increased T cell derived lymphoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002024I129S2SvPasTrp53tm1TyjTrp53tm1TyjTrp53tm1Tyj
• abnormal embryo development_Ino80<tm1.1Schg>/Ino80<tm1.1Schg>
  http://metadb.riken.jp/0001672IC57BL6JIno80tm11SchgIno80tm11SchgIno80tm11Schg
• preweaning lethality, complete penetrance_Ino80<tm1.1Schg>/Ino80<tm1.1Schg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0011100I129S2SvPasC57BL6JIno80tm11SchgIno80tm11SchgTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjIno80tm11Schg
• abnormal cell physiology_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0005621IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• decreased body size_Ino80<tm1.1Schg>/Ino80<+>
  http://metadb.riken.jp/0001265IC57BL6JIno80tm11SchgIno80Ino80Ino80tm11Schg
• increased sarcoma incidence_Ino80<tm1.1Schg>/Ino80<+>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002032I129S2SvPasC57BL6JIno80tm11SchgIno80Trp53tm1TyjTrp53tm1TyjIno80tm11SchgTrp53tm1TyjIno80
• increased cellular sensitivity to alkylating agents_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008402IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• increased cellular sensitivity to hydroxyurea_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008409IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• abnormal cell cycle_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003077IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• decreased lymphoma incidence_Ino80<tm1.1Schg>/Ino80<+>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0010268I129S2SvPasC57BL6JIno80tm11SchgIno80Trp53tm1TyjTrp53tm1TyjIno80tm11SchgTrp53tm1TyjIno80
• early cellular replicative senescence_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008008IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• increased T cell derived lymphoma incidence_Ino80<tm1.1Schg>/Ino80<+>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002024I129S2SvPasC57BL6JIno80tm11SchgIno80Trp53tm1TyjTrp53tm1TyjIno80tm11SchgTrp53tm1TyjIno80
• increased cellular sensitivity to ultraviolet irradiation_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008410IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• decreased fibroblast proliferation_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0011704IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• increased lymphoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0012431I129S2SvPasTrp53tm1TyjTrp53tm1TyjTrp53tm1Tyj
• abnormal double-strand DNA break repair_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0010948IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg
• abnormal response to radiation_Ino80<tm1Schg>/Ino80<tm1Schg>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0012734IC57BL6CBAIno80tm1SchgIno80tm1SchgTgCAGcreEsr15Amc0TgCAGcreEsr15AmcIno80tm1Schg