increased leukemia incidence_Pml<tm1(PML/RARA)Ley>/Pml<+>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0002026I129P2OlaHsdBALBcJC57BL6Pmltm1PMLRARALeyPmlLyz2tm1creIfoLyz2Lyz2PmlLyz2tm1creIfoPmltm1PMLRARALey

increased leukemia incidence_Pml<tm1(PML/RARA)Ley>/Pml<+>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897
• promyelocytic leukemia
  http://metadb.riken.jp/db/mgi_rdf/MGI:104662

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pml<tm1(PML/RARA)Ley>/Pml<+>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyz2<+>|Pml<+>|Lyz2<tm1(cre)Ifo>|Pml<tm1(PML/RARA)Ley>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased leukemia incidence
  http://purl.obolibrary.org/obo/MP_0002026

文献

http://purl.org/net/cito/citesAsAuthority

• John S. Welch, et.al., PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/21364283