increased leukemia incidence_Col1a1<tm1(CAG-Mir22)Ppp>/Col1a1<tm1(CAG-Mir22)Ppp>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0002026NSCol1a1tm1CAGMir22PppCol1a1tm1CAGMir22PppTgMx1cre1Cgn0Col1a1tm1CAGMir22PppTgMx1cre1Cgn

increased leukemia incidence_Col1a1<tm1(CAG-Mir22)Ppp>/Col1a1<tm1(CAG-Mir22)Ppp>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm1(CAG-Mir22)Ppp>/Col1a1<tm1(CAG-Mir22)Ppp>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Col1a1<tm1(CAG-Mir22)Ppp>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• Not Specified

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased leukemia incidence
  http://purl.obolibrary.org/obo/MP_0002026

文献

http://purl.org/net/cito/citesAsAuthority

• Su Jung. Song, et.al., The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation., Cell stem cell, 2013, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/23827711