increased lung adenocarcinoma incidence_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-EGFR*T790M)8Paow/0

http://metadb.riken.jp/0002027I129C57BL6FVBNTgScgb1a1rtTA1Jaw0TgtetOEGFRT790M8Paow0TgtetOEGFRT790M8PaowTgScgb1a1rtTA1Jaw

increased lung adenocarcinoma incidence_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-EGFR*T790M)8Paow/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 8, William Pao
  http://metadb.riken.jp/db/mgi_rdf/MGI:5705247
• transgene insertion 1, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:2652186

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-EGFR*T790M)8Paow/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-EGFR*T790M)8Paow|Tg(Scgb1a1-rtTA)1Jaw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002027

文献

http://purl.org/net/cito/citesAsAuthority

• Lucia. Regales, et.al., Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors., PloS one, 2007, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/17726540