Lucia. Regales, et.al., Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors., PloS one, 2007, 2

http://rdf.ncbi.nlm.nih.gov/pubmed/17726540

Lucia. Regales, et.al., Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors., PloS one, 2007, 2

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-EGFR*T790M*L858R)51Paow
  http://metadb.riken.jp/db/mgi_rdf/MGI:5705251
• Tg(tetO-EGFR*T790M)8Paow
  http://metadb.riken.jp/db/mgi_rdf/MGI:5705250

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• tachypnea_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-EGFR*T790M*L858R)51Paow/0
  http://metadb.riken.jp/0005426I129C57BL6FVBNTgScgb1a1rtTA1Jaw0TgtetOEGFRT790ML858R51Paow0TgtetOEGFRT790ML858R51PaowTgScgb1a1rtTA1Jaw
• increased lung adenocarcinoma incidence_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-EGFR*T790M*L858R)51Paow/0
  http://metadb.riken.jp/0002027I129C57BL6FVBNTgScgb1a1rtTA1Jaw0TgtetOEGFRT790ML858R51Paow0TgtetOEGFRT790ML858R51PaowTgScgb1a1rtTA1Jaw
• increased lung adenocarcinoma incidence_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-EGFR*T790M)8Paow/0
  http://metadb.riken.jp/0002027I129C57BL6FVBNTgScgb1a1rtTA1Jaw0TgtetOEGFRT790M8Paow0TgtetOEGFRT790M8PaowTgScgb1a1rtTA1Jaw
• increased lung adenocarcinoma incidence_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-EGFR*L858R)#Hev/0
  http://metadb.riken.jp/0002027I129C57BL6CBATgScgb1a1rtTA1Jaw0TgtetOEGFRL858RHev0TgScgb1a1rtTA1JawTgtetOEGFRL858RHev

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-EGFR*T790M*L858R)51Paow
  http://metadb.riken.jp/db/mgi_rdf/MGI:5705251
• Tg(tetO-EGFR*T790M)8Paow
  http://metadb.riken.jp/db/mgi_rdf/MGI:5705250