increased lung adenocarcinoma incidence_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-PIK3CA*H1047R)13Lca/0

http://metadb.riken.jp/0002027I129C57BL6FVBNTgScgb1a1rtTA1Jaw0TgtetOPIK3CAH1047R13Lca0TgtetOPIK3CAH1047R13LcaTgScgb1a1rtTA1Jaw

increased lung adenocarcinoma incidence_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-PIK3CA*H1047R)13Lca/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:2652186
• transgene insertion 13, Lewis C Cantley
  http://metadb.riken.jp/db/mgi_rdf/MGI:3834438

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-PIK3CA*H1047R)13Lca/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-PIK3CA*H1047R)13Lca|Tg(Scgb1a1-rtTA)1Jaw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002027

文献

http://purl.org/net/cito/citesAsAuthority

• Jeffrey A. Engelman, et.al., Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers., Nature medicine, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/19029981