increased lung adenocarcinoma incidence_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>,Trp53<tm1Tyj>/Trp53<+>

http://metadb.riken.jp/0002027I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynTrp53tm1TyjTrp53Trp53tm1TyjThbs1tm1HynTrp53

increased lung adenocarcinoma incidence_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>,Trp53<tm1Tyj>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• thrombospondin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98737

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Thbs1<tm1Hyn>/Thbs1<tm1Hyn>,Trp53<tm1Tyj>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>|Thbs1<tm1Hyn>|Trp53<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002027

文献

http://purl.org/net/cito/citesAsAuthority

• J. Lawler, et.al., Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice., The American journal of pathology, 2001, 159
  http://rdf.ncbi.nlm.nih.gov/pubmed/11696456