increased neurofibrosarcoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<+>,Nf1<tm1Tyj>/Nf1<+>

http://metadb.riken.jp/0002030I129S2SvPas129S6SvEvTacCdkn2atm1RdpCdkn2aNf1tm1TyjNf1Nf1tm1TyjCdkn2atm1RdpNf1Cdkn2a

increased neurofibrosarcoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<+>,Nf1<tm1Tyj>/Nf1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• neurofibromin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97306
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<+>,Nf1<tm1Tyj>/Nf1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nf1<tm1Tyj>|Cdkn2a<tm1Rdp>|Nf1<+>|Cdkn2a<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S6/SvEvTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased neurofibrosarcoma incidence
  http://purl.obolibrary.org/obo/MP_0002030

文献

http://purl.org/net/cito/citesAsAuthority

• Nancy M. Joseph, et.al., The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells., Cancer cell, 2008, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/18242513