Nancy M. Joseph, et.al., The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells., Cancer cell, 2008, 13

http://rdf.ncbi.nlm.nih.gov/pubmed/18242513

Nancy M. Joseph, et.al., The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells., Cancer cell, 2008, 13

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Postn-cre)1Sjc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3775923

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased neurofibrosarcoma incidence_Nf1<tm1Tyj>/Nf1<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002030I129S2SvPasNf1tm1TyjNf1Trp53tm1TyjTrp53Nf1Nf1tm1TyjTrp53Trp53tm1Tyj
• increased lymphoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Nf1<tm1Tyj>/Nf1<+>
  http://metadb.riken.jp/0012431I129S2SvPas129S6SvEvTacCdkn2atm1RdpCdkn2atm1RdpNf1tm1TyjNf1Nf1tm1TyjNf1Cdkn2atm1Rdp
• increased neurofibroma incidence_Nf1<tm1Par>/Nf1<tm1Tyj>,Tg(P0-Cre)1Gth/0
  http://metadb.riken.jp/0010314I129SvFVBNNf1tm1ParNf1tm1TyjTgP0Cre1Gth0Nf1tm1TyjTgP0Cre1GthNf1tm1Par
• premature death_Nf1<tm1Par>/Nf1<tm1Tyj>,Tg(Postn-cre)1Sjc/0
  http://metadb.riken.jp/0002083I129S1Sv129S2SvPas129X1SvJNf1tm1ParNf1tm1TyjTgPostncre1Sjc0Nf1tm1TyjNf1tm1ParTgPostncre1Sjc
• increased leukemia incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Nf1<tm1Tyj>/Nf1<+>
  http://metadb.riken.jp/0002026I129S2SvPas129S6SvEvTacCdkn2atm1RdpCdkn2atm1RdpNf1tm1TyjNf1Nf1tm1TyjNf1Cdkn2atm1Rdp
• increased neurofibrosarcoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<+>,Nf1<tm1Tyj>/Nf1<+>
  http://metadb.riken.jp/0002030I129S2SvPas129S6SvEvTacCdkn2atm1RdpCdkn2aNf1tm1TyjNf1Nf1tm1TyjCdkn2atm1RdpNf1Cdkn2a
• abnormal neural crest cell morphology_Nf1<tm1Par>/Nf1<tm1Tyj>,Tg(Postn-cre)1Sjc/0
  http://metadb.riken.jp/0009845I129S1Sv129S2SvPas129X1SvJNf1tm1ParNf1tm1TyjTgPostncre1Sjc0Nf1tm1TyjNf1tm1ParTgPostncre1Sjc
• increased lymphoma incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Nf1<tm1Tyj>/Nf1<+>
  http://metadb.riken.jp/0012431I129S2SvPas129S6SvEvTacCdkn2atm21RdpCdkn2atm21RdpNf1tm1TyjNf1Cdkn2atm21RdpNf1tm1TyjNf1
• premature death_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Nf1<tm1Tyj>/Nf1<+>
  http://metadb.riken.jp/0002083I129S2SvPas129S6SvEvTacCdkn2atm1RdpCdkn2atm1RdpNf1tm1TyjNf1Nf1tm1TyjNf1Cdkn2atm1Rdp
• increased neurofibrosarcoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Nf1<tm1Tyj>/Nf1<+>
  http://metadb.riken.jp/0002030I129S2SvPas129S6SvEvTacCdkn2atm1RdpCdkn2atm1RdpNf1tm1TyjNf1Nf1tm1TyjNf1Cdkn2atm1Rdp
• abnormal neural crest cell morphology_Nf1<tm1Par>/Nf1<tm1Tyj>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0009845I129SvC57BL6CBANf1tm1ParNf1tm1TyjTgWnt1cre11Rth0Nf1tm1ParNf1tm1TyjTgWnt1cre11Rth
• abnormal neural crest cell morphology_Nf1<tm1Tyj>/Nf1<tm1Tyj>
  http://metadb.riken.jp/0009845I129S2SvPasNf1tm1TyjNf1tm1TyjNf1tm1Tyj

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Postn-cre)1Sjc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3775923