increased adrenal gland tumor incidence_Grb2<tm1Paw>/Grb2<+>,Pten<tm1Mak>/Pten<+>

http://metadb.riken.jp/0002031I129P2OlaHsd129S1Sv129X1SvJC57BL6Grb2tm1PawGrb2Ptentm1MakPtenPtentm1MakGrb2tm1PawGrb2Pten

increased adrenal gland tumor incidence_Grb2<tm1Paw>/Grb2<+>,Pten<tm1Mak>/Pten<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• growth factor receptor bound protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95805
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grb2<tm1Paw>/Grb2<+>,Pten<tm1Mak>/Pten<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Mak>|Grb2<tm1Paw>|Grb2<+>|Pten<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased adrenal gland tumor incidence
  http://purl.obolibrary.org/obo/MP_0002031

文献

http://purl.org/net/cito/citesAsAuthority

• Megan. Cully, et.al., grb2 heterozygosity rescues embryonic lethality but not tumorigenesis in pten+/- mice., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/15492213