Megan. Cully, et.al., grb2 heterozygosity rescues embryonic lethality but not tumorigenesis in pten+/- mice., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101

http://rdf.ncbi.nlm.nih.gov/pubmed/15492213

Megan. Cully, et.al., grb2 heterozygosity rescues embryonic lethality but not tumorigenesis in pten+/- mice., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• failure of chorioallantoic fusion_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0009657B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak
• increased endometrial carcinoma incidence_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0004868B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak
• increased adrenal gland tumor incidence_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0002031B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak
• abnormal embryonic tissue morphology_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0002085B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak
• increased endometrial carcinoma incidence_Grb2<tm1Paw>/Grb2<+>,Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0004868I129P2OlaHsd129S1Sv129X1SvJC57BL6Grb2tm1PawGrb2Ptentm1MakPtenPtentm1MakGrb2tm1PawGrb2Pten
• failure of initiation of embryo turning_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0004180B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak
• open neural tube_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0000929B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak
• kinked neural tube_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0003400B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak
• increased T cell derived lymphoma incidence_Grb2<tm1Paw>/Grb2<+>,Pten<tm2Mak>/Pten<tm2Mak>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0002024I129P2OlaHsdC57BL6CBAGrb2tm1PawGrb2Ptentm2MakPtentm2MakTgLckcre548Jxm0Ptentm2MakTgLckcre548JxmGrb2tm1PawGrb2
• abnormal placenta morphology_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0001711B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak
• increased adrenal gland tumor incidence_Grb2<tm1Paw>/Grb2<+>,Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0002031I129P2OlaHsd129S1Sv129X1SvJC57BL6Grb2tm1PawGrb2Ptentm1MakPtenPtentm1MakGrb2tm1PawGrb2Pten
• decreased embryo size_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0001698B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak
• increased tumor incidence_Grb2<tm1Paw>/Grb2<+>,Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0002020I129P2OlaHsd129S1Sv129X1SvJC57BL6Grb2tm1PawGrb2Ptentm1MakPtenPtentm1MakGrb2tm1PawGrb2Pten
• increased lymphoma incidence_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0012431B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak
• increased lymphoma incidence_Grb2<tm1Paw>/Grb2<+>,Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0012431I129P2OlaHsd129S1Sv129X1SvJC57BL6Grb2tm1PawGrb2Ptentm1MakPtenPtentm1MakGrb2tm1PawGrb2Pten
• increased tumor incidence_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0002020B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak
• enlarged allantois_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0004556B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak
• embryonic lethality during organogenesis, incomplete penetrance_Pten<tm1Mak>/Pten<+>
  http://metadb.riken.jp/0011108B6129P2Ptentm1MakPtentm1MakPtenPtenPtentm1Mak