increased sarcoma incidence_Kras<tm5Tyj>/Kras<+>,Trp53<tm1.1Dgk>/Trp53<tm1.1Dgk>

http://metadb.riken.jp/0002032I129S1Sv129S4SvJaeSor129X1SvJC57BL6Krastm5TyjKrasTrp53tm11DgkTrp53tm11DgkTrp53tm11DgkKrasKrastm5Tyj

increased sarcoma incidence_Kras<tm5Tyj>/Kras<+>,Trp53<tm1.1Dgk>/Trp53<tm1.1Dgk>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm5Tyj>/Kras<+>,Trp53<tm1.1Dgk>/Trp53<tm1.1Dgk>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1.1Dgk>|Kras<+>|Kras<tm5Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sarcoma incidence
  http://purl.obolibrary.org/obo/MP_0002032

文献

http://purl.org/net/cito/citesAsAuthority

• Chang-Lung. Lee, et.al., Generation of primary tumors with Flp recombinase in FRT-flanked p53 mice., Disease models & mechanisms, 2012, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/22228755