Chang-Lung. Lee, et.al., Generation of primary tumors with Flp recombinase in FRT-flanked p53 mice., Disease models & mechanisms, 2012, 5

http://rdf.ncbi.nlm.nih.gov/pubmed/22228755

Chang-Lung. Lee, et.al., Generation of primary tumors with Flp recombinase in FRT-flanked p53 mice., Disease models & mechanisms, 2012, 5

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Trp53<tm1.1Dgk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5306612

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• delayed cellular replicative senescence_Trp53<tm1Tyj>/Trp53<tm1.1Dgk>
  http://metadb.riken.jp/0008009I129S129X1SvJC57BL6Trp53tm1TyjTrp53tm11DgkTrp53tm1TyjTrp53tm11Dgk
• increased tumor growth/size_Kras<tm5Tyj>/Kras<+>,Trp53<tm1.1Dgk>/Trp53<tm1.1Dgk>
  http://metadb.riken.jp/0003721I129S1Sv129S4SvJaeSor129X1SvJC57BL6Krastm5TyjKrasTrp53tm11DgkTrp53tm11DgkTrp53tm11DgkKrasKrastm5Tyj
• increased cell proliferation_Trp53<tm1Tyj>/Trp53<tm1.1Dgk>
  http://metadb.riken.jp/0000351I129S129X1SvJC57BL6Trp53tm1TyjTrp53tm11DgkTrp53tm1TyjTrp53tm11Dgk
• increased sarcoma incidence_Kras<tm5Tyj>/Kras<+>,Trp53<tm1.1Dgk>/Trp53<tm1.1Dgk>
  http://metadb.riken.jp/0002032I129S1Sv129S4SvJaeSor129X1SvJC57BL6Krastm5TyjKrasTrp53tm11DgkTrp53tm11DgkTrp53tm11DgkKrasKrastm5Tyj
• increased lung adenocarcinoma incidence_Kras<tm5Tyj>/Kras<+>,Trp53<tm1.1Dgk>/Trp53<tm1.1Dgk>
  http://metadb.riken.jp/0002027I129S1Sv129S4SvJaeSor129X1SvJC57BL6Krastm5TyjKrasTrp53tm11DgkTrp53tm11DgkTrp53tm11DgkKrasKrastm5Tyj

class

http://purl.org/net/cito/citesAsAuthority

• Trp53<tm1.1Dgk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5306612