increased sarcoma incidence_Trp53<tm1Tyj>/Trp53<+>,Trp73<tm1Fmc>/Trp73<+>

http://metadb.riken.jp/0002032I129S2SvPas129S4SvJaeC57BL6Trp53tm1TyjTrp53Trp73tm1FmcTrp73Trp73Trp73tm1FmcTrp53Trp53tm1Tyj

increased sarcoma incidence_Trp53<tm1Tyj>/Trp53<+>,Trp73<tm1Fmc>/Trp73<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 73
  http://metadb.riken.jp/db/mgi_rdf/MGI:1336991
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Tyj>/Trp53<+>,Trp73<tm1Fmc>/Trp73<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp73<+>|Trp73<tm1Fmc>|Trp53<+>|Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sarcoma incidence
  http://purl.obolibrary.org/obo/MP_0002032

文献

http://purl.org/net/cito/citesAsAuthority

• Elsa R. Flores, et.al., Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family., Cancer cell, 2005, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/15837625