increased rhabdomyosarcoma incidence_Cdkn1b<tm1Mlf>/Cdkn1b<+>,Ptch1<tm1Mps>/Ptch1<+>

http://metadb.riken.jp/0002036I129S1Sv129S4SvJaeSor129X1SvJC57BL6Cdkn1btm1MlfCdkn1bPtch1tm1MpsPtch1Ptch1Ptch1tm1MpsCdkn1bCdkn1btm1Mlf

increased rhabdomyosarcoma incidence_Cdkn1b<tm1Mlf>/Cdkn1b<+>,Ptch1<tm1Mps>/Ptch1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• patched 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:105373
• cyclin-dependent kinase inhibitor 1B
  http://metadb.riken.jp/db/mgi_rdf/MGI:104565

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1b<tm1Mlf>/Cdkn1b<+>,Ptch1<tm1Mps>/Ptch1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptch1<+>|Ptch1<tm1Mps>|Cdkn1b<+>|Cdkn1b<tm1Mlf>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased rhabdomyosarcoma incidence
  http://purl.obolibrary.org/obo/MP_0002036

文献

http://purl.org/net/cito/citesAsAuthority

• Olivier. Ayrault, et.al., Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma., Molecular cancer research : MCR, 2009, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/19147535